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T cell response to intact SARS-CoV-2 includes coronavirus cross-reactive and variant-specific components

SARS-CoV-2 provokes a robust T cell response. Peptide-based studies exclude antigen processing and presentation biology, which may influence T cell detection studies. To focus on responses to whole virus and complex antigens, we used intact SARS-CoV-2 and full-length proteins with DCs to activate CD...

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Detalles Bibliográficos
Autores principales:	Jing, Lichen, Wu, Xia, Krist, Maxwell P., Hsiang, Tien-Ying, Campbell, Victoria L., McClurkan, Christopher L., Favors, Sydney M., Hemingway, Lawrence A., Godornes, Charmie, Tong, Denise Q., Selke, Stacy, LeClair, Angela C., Pyo, Chu-Woo, Geraghty, Daniel E., Laing, Kerry J., Wald, Anna, Gale, Michael, Koelle, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986086/ https://www.ncbi.nlm.nih.gov/pubmed/35133988 http://dx.doi.org/10.1172/jci.insight.158126

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