Non-human primate papillomavirus E6-mediated p53 degradation reveals ancient evolutionary adaptation of carcinogenic phenotype to host niche

Non-human primates (NHPs) are infected with papillomaviruses (PVs) closely related to their human counterparts, but there are few studies on the carcinogenicity of NHP-PVs. Using an in vitro cell co-transfection assay, we systematically screened the biochemical activity of E6 proteins encoded by mac...

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Detalles Bibliográficos
Autores principales: Long, Teng, Burk, Robert D., Chan, Paul K. S., Chen, Zigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986119/
https://www.ncbi.nlm.nih.gov/pubmed/35333912
http://dx.doi.org/10.1371/journal.ppat.1010444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986119/
https://www.ncbi.nlm.nih.gov/pubmed/35333912
http://dx.doi.org/10.1371/journal.ppat.1010444

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