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A controlled release bupivacaine-alginate construct: Effect on chondrocyte hypertrophy conversion

OBJECTIVE: Osteoarthritis is a degenerative disease of the joint, affecting over 30 million people in the US(1). A key characteristic of OA is chondrocyte hypertrophy, characterized by chondrocyte changes to a more rounded and osteoblastic phenotype, characterized by increased IL-6 and IL-8 secretio...

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Detalles Bibliográficos
Autores principales: Davis, Mollie S., Marrero – Berrios, Ileana, Perez, Xiomara I., Radhakrishnan, Palangat, Manchikalapati, Devasena, Ahmed, Khaja, Kamath, Hattiyangangadi, Schloss, Rene S., Yarmush, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986124/
https://www.ncbi.nlm.nih.gov/pubmed/35392127
http://dx.doi.org/10.1016/j.ocarto.2020.100125