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A controlled release bupivacaine-alginate construct: Effect on chondrocyte hypertrophy conversion
OBJECTIVE: Osteoarthritis is a degenerative disease of the joint, affecting over 30 million people in the US(1). A key characteristic of OA is chondrocyte hypertrophy, characterized by chondrocyte changes to a more rounded and osteoblastic phenotype, characterized by increased IL-6 and IL-8 secretio...
Autores principales: | Davis, Mollie S., Marrero – Berrios, Ileana, Perez, Xiomara I., Radhakrishnan, Palangat, Manchikalapati, Devasena, Ahmed, Khaja, Kamath, Hattiyangangadi, Schloss, Rene S., Yarmush, Joel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986124/ https://www.ncbi.nlm.nih.gov/pubmed/35392127 http://dx.doi.org/10.1016/j.ocarto.2020.100125 |
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