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High-cited favorable studies for COVID-19 treatments ineffective in large trials

OBJECTIVES: To evaluate for coronavirus disease 2019 treatments without benefits in subsequent large randomized controlled trials (RCTs) how many of their most-cited clinical studies had declared favorable results. STUDY DESIGN AND SETTING: Scopus searches (December 23, 2021) identified articles on...

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Detalles Bibliográficos
Autor principal: Ioannidis, John P.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986133/
https://www.ncbi.nlm.nih.gov/pubmed/35398190
http://dx.doi.org/10.1016/j.jclinepi.2022.04.001