Cargando…

PD-L1 blockade potentiates the antitumor effects of ALA-PDT and optimizes the tumor microenvironment in cutaneous squamous cell carcinoma

Immune checkpoint blockade (ICB) is a powerful oncologic treatment modality for a wide variety of human malignancies, but the patient response rate to this treatment remains low, especially in patients with cutaneous squamous cell carcinoma (cSCC). 5-Aminoleuvulinic acid-photodynamic therapy (ALA-PD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Qingyu, Yang, Jiayi, Ji, Jie, Wang, Peiru, Zhang, Linglin, Yan, Guorong, Wu, Yuhao, Chen, Qi, Liu, Jia, Zhang, Guolong, Wang, Xiuli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986186/ https://www.ncbi.nlm.nih.gov/pubmed/35402079 http://dx.doi.org/10.1080/2162402X.2022.2061396

Ejemplares similares

Antitumor Effects of DC Vaccine With ALA-PDT-Induced Immunogenic Apoptotic Cells for Skin Squamous Cell Carcinoma in Mice
por: Zhang, Haiyan, et al.
Publicado: (2018)

Improvement of DC vaccine with ALA-PDT induced immunogenic apoptotic cells for skin squamous cell carcinoma
por: Ji, Jie, et al.
Publicado: (2015)

Stimulation of dendritic cells by DAMPs in ALA-PDT treated SCC tumor cells
por: Wang, Xiaojie, et al.
Publicado: (2015)

Single cell transcriptome profiling reveals cutaneous immune microenvironment remodeling by photodynamic therapy in photoaged skin
por: Yan, Yu, et al.
Publicado: (2023)

NLRP3 Inflammasome Mediated Interleukin-1β Production in Cancer-Associated Fibroblast Contributes to ALA-PDT for Cutaneous Squamous Cell Carcinoma
por: Nie, Shu, et al.
Publicado: (2019)

DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma
por: Ji, Jie, et al.
Publicado: (2015)

Single-cell transcriptomic analysis reveals the critical molecular pattern of UV-induced cutaneous squamous cell carcinoma
por: Yan, Guorong, et al.
Publicado: (2021)

Monitoring blood flow responses during topical ALA-PDT
por: Becker, Theresa L., et al.
Publicado: (2010)

Modified 5-aminolevulinic acid photodynamic therapy suppresses cutaneous squamous cell carcinoma through blocking Akt/mTOR-mediated autophagic flux
por: Zeng, Qingyu, et al.
Publicado: (2023)

Case Report: Diverse phenotypes of congenital poikiloderma associated with FAM111B mutations in codon 628: A case report and literature review
por: Wu, Yuhao, et al.
Publicado: (2022)

Effect and Safety of ALA-PDT Combined with 1550 nm Fractional Therapy Laser in Treating Rosacea
por: Wang, Hefei, et al.
Publicado: (2022)

ALA_PDT Promotes Ferroptosis-Like Death of Mycobacterium abscessus and Antibiotic Sterilization via Oxidative Stress
por: Wang, Xiaoyu, et al.
Publicado: (2022)

Topical 5-aminolevulinic photodynamic therapy with red light vs intense pulsed light for the treatment of acne vulgaris: A spilit face, randomized, prospective study
por: Zhang, Linglin, et al.
Publicado: (2017)

Effects of ALA-PDT on the Healing of Mouse Skin Wounds Infected With Pseudomonas aeruginosa and Its Related Mechanisms
por: Yang, Tao, et al.
Publicado: (2020)

Photodynamic therapy combined with antifungal drugs against chromoblastomycosis and the effect of ALA-PDT on Fonsecaea in vitro
por: Hu, Yongxuan, et al.
Publicado: (2019)

Efficacy of 5-Aminolevulinic Acid (ALA)-Photodynamic Therapy (PDT) in Refractory Vulvar Lichen Sclerosus: Preliminary Results
por: Zhang, Fenghua, et al.
Publicado: (2021)

Exploring the Pathogenesis and Mechanism-Targeted Treatments of Rosacea: Previous Understanding and Updates
por: Chen, Chengqian, et al.
Publicado: (2023)

Predictive biomarkers for 5‐ALA‐PDT can lead to personalized treatments and overcome tumor‐specific resistances
por: Mastrangelopoulou, Maria, et al.
Publicado: (2020)

Retracted: Effect and Safety of ALA-PDT Combined with 1550 nm Fractional Therapy Laser in Treating Rosacea
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment
por: Fang, Douglas D., et al.
Publicado: (2019)

A case series pilot study on the combination of 5-aminolevulinic acid and photodynamic therapy (ALA-PDT) for treatment of vitiligo
por: Zhang, YunJie, et al.
Publicado: (2018)

Treating cutaneous squamous cell carcinoma using 5-aminolevulinic acid polylactic-co-glycolic acid nanoparticle-mediated photodynamic therapy in a mouse model
por: Wang, Xiaojie, et al.
Publicado: (2015)

Photodynamic Therapy (PDT): PDT Mechanisms
por: Allison, Ron R., et al.
Publicado: (2013)

Genomic features and tumor immune microenvironment alteration in NSCLC treated with neoadjuvant PD-1 blockade
por: Wang, Shuhang, et al.
Publicado: (2022)

5-ALA Fluorescence in Native Pituitary Adenoma Cell Lines: Resection Control and Basis for Photodynamic Therapy (PDT)?
por: Nemes, Andrei, et al.
Publicado: (2016)

Clinical evaluation of smartphone-based fluorescence imaging for guidance and monitoring of ALA-PDT treatment of early oral cancer
por: Khan, Shakir, et al.
Publicado: (2020)

Multifunctional Nanoparticles-Mediated PTT/PDT Synergistic Immune Activation and Antitumor Activity Combined with Anti-PD-L1 Immunotherapy for Breast Cancer Treatment
por: Kong, Cunqing, et al.
Publicado: (2022)

A new optical intra-tissue fiber irradiation ALA-PDT in the treatment of acne vulgaris in rabbit model: improved safety and tolerability
por: Wang, Qian, et al.
Publicado: (2017)

PDT Chinois
Publicado: (1999)

Whole genome methylation sequencing reveals epigenetic landscape and abnormal expression of FABP5 in extramammary Paget's disease
por: Kang, Ziwei, et al.
Publicado: (2023)

Clinical and Molecular Characterization of NF1 Patients: Single-Center Experience of 32 Patients From China
por: Zhu, Lude, et al.
Publicado: (2016)

Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity
por: Zhang, Yuankun, et al.
Publicado: (2023)

PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?
por: Xu-Monette, Zijun Y., et al.
Publicado: (2017)

FABP7 inhibits proliferation and invasion abilities of cutaneous squamous cell carcinoma cells via the Notch signaling pathway
por: Sun, Zhonghui, et al.
Publicado: (2022)

Epigallocatechin Gallate Enhances MAL-PDT Cytotoxic Effect on PDT-Resistant Skin Cancer Squamous Cells
por: León, Daniela, et al.
Publicado: (2020)

Correlation of the ALA-PDT Treatment Efficacy and the HPV Genotype Profile of Genital Warts after Cryotherapy Failure and Podophyllotoxin Therapy in Male Patients
por: Owczarek, Witold, et al.
Publicado: (2021)

Selective targeting of GARP-LTGFβ axis in the tumor microenvironment augments PD-1 blockade via enhancing CD8(+) T cell antitumor immunity
por: Li, Anqi, et al.
Publicado: (2022)

Effect of photodynamic therapy (PDT), posterior subtenon injection of triamcinolone acetonide with PDT, and intravitreal injection of ranibizumab with PDT for retinal angiomatous proliferation
por: Nakano, Saya, et al.
Publicado: (2012)

Identification of Therapeutic Targets and Prognostic Biomarkers Among Integrin Subunits in the Skin Cutaneous Melanoma Microenvironment
por: Nurzat, Yeltai, et al.
Publicado: (2021)

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM
por: Hung, Alice L., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gdf7ovdrsb916ibkcfpsdl3qlq