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Handling death as an intercurrent event in time to recovery analysis in COVID-19 treatment clinical trials

In clinical trials with the objective to evaluate the treatment effect on time to recovery, such as investigational trials on therapies for COVID-19 hospitalized patients, the patients may face a mortality risk that competes with the opportunity to recover (e.g., be discharged from the hospital). Th...

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Detalles Bibliográficos
Autores principales: Li, Hong, Gleason, Kevin J., Hu, Yiran, Lovell, Sandra S., Mukhopadhyay, Saurabh, Wang, Li, Huang, Bidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986229/
https://www.ncbi.nlm.nih.gov/pubmed/35398251
http://dx.doi.org/10.1016/j.cct.2022.106758