Cargando…

TSPO Ligands Protect against Neuronal Damage Mediated by LPS-Induced BV-2 Microglia Activation

Neuroinflammation is a critical pathological process of neurodegenerative diseases, and alleviating the inflammatory response caused by abnormally activated microglia might be valuable for treatment. The 18 kDa translocator protein (TSPO), a biomarker of neuroinflammation, is significantly elevated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Baoyu, Liu, Yongxin, Zhang, Xiao, Zhang, Rui, Zhang, Zhenjiang, Zhang, Zhihao, Liu, Jie, Juan, Zhaodong, Sun, Xiaotong, Sun, Lina, Huang, Jingyao, Feng, Jinpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986436/ https://www.ncbi.nlm.nih.gov/pubmed/35401924 http://dx.doi.org/10.1155/2022/5896699

Ejemplares similares

The TSPO-specific Ligand PK11195 Protects Against LPS-Induced Cognitive Dysfunction by Inhibiting Cellular Autophagy
por: Lan, Nannan, et al.
Publicado: (2021)

TSPO Ligands PK11195 and Midazolam Reduce NLRP3 Inflammasome Activation and Proinflammatory Cytokine Release in BV-2 Cells
por: Feng, Hao, et al.
Publicado: (2020)

Translocator Protein 18 kDa (TSPO) as a Novel Therapeutic Target for Chronic Pain
por: Liu, Jie, et al.
Publicado: (2022)

Mesenchymal Stem Cell-Derived Exosomes Ameliorate Delayed Neurocognitive Recovery in Aged Mice by Inhibiting Hippocampus Ferroptosis via Activating SIRT1/Nrf2/HO-1 Signaling Pathway
por: Liu, Jie, et al.
Publicado: (2022)

The TSPO Ligands 2-Cl-MGV-1, MGV-1, and PK11195 Differentially Suppress the Inflammatory Response of BV-2 Microglial Cell to LPS
por: Azrad, Maya, et al.
Publicado: (2019)

The Efficacy of the Novel TSPO Ligands 2-Cl-MGV-1 and 2,4-Di-Cl-MGV-1 Compared to the Classical TSPO Ligand PK 11195 to Counteract the Release of Chemokines from LPS-Stimulated BV-2 Microglial Cells
por: Monga, Sheelu, et al.
Publicado: (2020)

Benfotiamine Attenuates Inflammatory Response in LPS Stimulated BV-2 Microglia
por: Bozic, Iva, et al.
Publicado: (2015)

Reduction of Traumatic Brain Damage by Tspo Ligand Etifoxine
por: Shehadeh, Mona, et al.
Publicado: (2019)

Dexmedetomidine Attenuates Neuroinflammation In LPS-Stimulated BV2 Microglia Cells Through Upregulation Of miR-340
por: Bao, Yang, et al.
Publicado: (2019)

Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia
por: Das, Amitabh, et al.
Publicado: (2016)

Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells
por: Zheng, Piao, et al.
Publicado: (2020)

Blueberry Counteracts BV-2 Microglia Morphological and Functional Switch after LPS Challenge
por: De Caris, Maria Giovanna, et al.
Publicado: (2020)

Response Profiles of BV2 Microglia to IFN-γ and LPS Co-Stimulation and Priming
por: Pan, Meng Liy, et al.
Publicado: (2023)

Ganoderic Acid A Attenuates LPS-Induced Neuroinflammation in BV2 Microglia by Activating Farnesoid X Receptor
por: Jia, Yue, et al.
Publicado: (2021)

Caspase-1 inhibition attenuates activation of BV2 microglia induced by LPS-treated RAW264.7 macrophages
por: Pan, Yang, et al.
Publicado: (2016)

Taraxasterol Inhibits LPS-Induced Inflammatory Response in BV2 Microglia Cells by Activating LXRα
por: Liu, Bin, et al.
Publicado: (2018)

6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ
por: Han, Qinghe, et al.
Publicado: (2017)

In vitro examination of microglia-neuron crosstalk with BV2 cells, and primary cultures of glia and hypothalamic neurons
por: Tao, Xinrong, et al.
Publicado: (2018)

Tetrathiomolybdate Treatment Leads to the Suppression of Inflammatory Responses through the TRAF6/NFκB Pathway in LPS-Stimulated BV-2 Microglia
por: Wang, Zhuo, et al.
Publicado: (2018)

Correction: 6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ
por: Han, Qinghe, et al.
Publicado: (2018)

miRNA expression profiles and molecular networks in resting and LPS-activated BV-2 microglia—Effect of cannabinoids
por: Juknat, Ana, et al.
Publicado: (2019)

Remifentanil inhibits the inflammatory response of BV2 microglia and protects PC12 cells from damage caused by microglia activation
por: Huang, Yankui, et al.
Publicado: (2022)

The protective effect of the TSPO ligands 2,4-Di-Cl-MGV-1, CB86, and CB204 against LPS-induced M1 pro-inflammatory activation of microglia
por: Monga, Sheelu, et al.
Publicado: (2020)

Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death
por: Zhang, Wenyou, et al.
Publicado: (2022)

Fucoxanthinol from the Diatom Nitzschia Laevis Ameliorates Neuroinflammatory Responses in Lipopolysaccharide-Stimulated BV-2 Microglia
por: Li, Yuelian, et al.
Publicado: (2020)

Molecular Mechanisms of the Anti-Inflammatory Effects of Epigallocatechin 3-Gallate (EGCG) in LPS-Activated BV-2 Microglia Cells
por: Payne, Ashley, et al.
Publicado: (2023)

Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells
por: Standoli, Sara, et al.
Publicado: (2023)

Antineuroinflammatory Activities and Neurotoxicological Assessment of Curcumin Loaded Solid Lipid Nanoparticles on LPS-Stimulated BV-2 Microglia Cell Models
por: Ganesan, Palanivel, et al.
Publicado: (2019)

Inhibitory Effects of the Two Novel TSPO Ligands 2-Cl-MGV-1 and MGV-1 on LPS-induced Microglial Activation
por: Monga, Sheelu, et al.
Publicado: (2019)

Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-κB and MAPK Pathways in LPS-Stimulated BV-2 Microglia
por: Li, Baojing, et al.
Publicado: (2022)

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease
por: Vicente-Rodríguez, Marta, et al.
Publicado: (2023)

T-2 Toxin Induces Apoptotic Cell Death and Protective Autophagy in Mouse Microglia BV2 Cells
por: Sun, Tun, et al.
Publicado: (2022)

Tetrapyrroles as Endogenous TSPO Ligands in Eukaryotes and Prokaryotes: Comparisons with Synthetic Ligands
por: Veenman, Leo, et al.
Publicado: (2016)

Upregulated TSG-6 Expression in ADSCs Inhibits the BV2 Microglia-Mediated Inflammatory Response
por: Hu, Yang, et al.
Publicado: (2018)

The effects of insulin on the inflammatory activity of BV2 microglia
por: Brabazon, Fiona, et al.
Publicado: (2018)

Neuroprotection by Skimmianine in Lipopolysaccharide-Activated BV-2 Microglia
por: Ogunrinade, Folashade A., et al.
Publicado: (2023)

TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis
por: Lejri, Imane, et al.
Publicado: (2019)

Inhibition of Autotaxin and Lysophosphatidic Acid Receptor 5 Attenuates Neuroinflammation in LPS-Activated BV-2 Microglia and a Mouse Endotoxemia Model
por: Joshi, Lisha, et al.
Publicado: (2021)

Minocycline and antipsychotics inhibit inflammatory responses in BV-2 microglia activated by LPS via regulating the MAPKs/ JAK-STAT signaling pathway
por: Long, Yujun, et al.
Publicado: (2023)

A Role of Fluoride on Free Radical Generation and Oxidative Stress in BV-2 Microglia Cells
por: Shuhua, Xi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_s9djne2nuh7rep6r1eiuch9l2c