Analysis of mRNA vaccination-elicited RBD-specific memory B cells reveals strong but incomplete immune escape of the SARS-CoV-2 Omicron variant

The SARS-CoV-2 Omicron variant can escape neutralization by vaccine-elicited and convalescent antibodies. Memory B cells (MBCs) represent another layer of protection against SARS-CoV-2, as they persist after infection and vaccination and improve their affinity. Whether MBCs elicited by mRNA vaccines...

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Autores principales: Sokal, Aurélien, Broketa, Matteo, Barba-Spaeth, Giovanna, Meola, Annalisa, Fernández, Ignacio, Fourati, Slim, Azzaoui, Imane, de La Selle, Andrea, Vandenberghe, Alexis, Roeser, Anais, Bouvier-Alias, Magali, Crickx, Etienne, Languille, Laetitia, Michel, Marc, Godeau, Bertrand, Gallien, Sébastien, Melica, Giovanna, Nguyen, Yann, Zarrouk, Virginie, Canoui-Poitrine, Florence, Noizat-Pirenne, France, Megret, Jérôme, Pawlotsky, Jean-Michel, Fillatreau, Simon, Simon-Lorière, Etienne, Weill, Jean-Claude, Reynaud, Claude-Agnès, Rey, Félix A., Bruhns, Pierre, Chappert, Pascal, Mahévas, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986479/
https://www.ncbi.nlm.nih.gov/pubmed/35483354
http://dx.doi.org/10.1016/j.immuni.2022.04.002

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