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Molecular mechanisms underlying the emergence of polygenetic antifungal drug resistance in msh2 mismatch repair mutants of Cryptococcus

BACKGROUND: Fungal infections are common life-threatening diseases amongst immunodeficient individuals. Invasive fungal disease is commonly treated with an azole antifungal agent, resulting in selection pressure and the emergence of drug resistance. Antifungal resistance is associated with higher mo...

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Detalles Bibliográficos
Autores principales:	Albehaijani, Samah H. I., Macreadie, Ian, Morrissey, C. Orla, Boyce, Kylie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986524/ https://www.ncbi.nlm.nih.gov/pubmed/35402912 http://dx.doi.org/10.1093/jacamr/dlac033

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