Genetic instability from a single S phase after whole-genome duplication

Diploid and stable karyotypes are associated with health and fitness in animals. By contrast, whole-genome duplications—doublings of the entire complement of chromosomes—are linked to genetic instability and frequently found in human cancers(1–3). It has been established that whole-genome duplicatio...

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Detalles Bibliográficos
Autores principales: Gemble, Simon, Wardenaar, René, Keuper, Kristina, Srivastava, Nishit, Nano, Maddalena, Macé, Anne-Sophie, Tijhuis, Andréa E., Bernhard, Sara Vanessa, Spierings, Diana C. J., Simon, Anthony, Goundiam, Oumou, Hochegger, Helfrid, Piel, Matthieu, Foijer, Floris, Storchová, Zuzana, Basto, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986533/
https://www.ncbi.nlm.nih.gov/pubmed/35355016
http://dx.doi.org/10.1038/s41586-022-04578-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986533/
https://www.ncbi.nlm.nih.gov/pubmed/35355016
http://dx.doi.org/10.1038/s41586-022-04578-4

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