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B2M and JAK1/2–mutated MSI-H Colorectal Carcinomas Can Benefit From Anti-PD-1 Therapy

β2-microglobulin (B2M) and Janus kinases 1 and 2 (JAK1/2) mutations have been suggested as genetic mechanisms of immune evasion for anti–programmed cell death protein 1 (PD-1) therapy. Whether B2M and JAK1/2 lose-of-function mutation can cause primary resistance to anti-PD-1 therapy in colorectal ca...

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Detalles Bibliográficos
Autores principales:	Zhang, Chenzhi, Li, Dandan, Xiao, Binyi, Zhou, Chi, Jiang, Wu, Tang, Jinghua, Li, Yuan, Zhang, Rongxin, Han, Kai, Hou, Zhenlin, Zhang, Linjie, Sui, Qiaoqi, Liao, Leen, Pan, Zhizhong, Zhang, Xiaoshi, Ding, Peirong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Basic Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986629/ https://www.ncbi.nlm.nih.gov/pubmed/35343934 http://dx.doi.org/10.1097/CJI.0000000000000417

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