SEOM—GECOD clinical guideline for unknown primary cancer (2021)

Cancer of unknown primary site (CUP) is defined as a heterogeneous group of tumors that appear as metastases, and of which standard diagnostic work-up fails to identify the origin. It is considered a separate entity with a specific biology, and nowadays molecular characteristics and the determinatio...

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Detalles Bibliográficos
Autores principales: Losa, Ferrán, Fernández, Isaura, Etxaniz, Olatz, Giménez, Alejandra, Gomila, Paula, Iglesias, Lara, Longo, Federico, Nogales, Esteban, Sánchez, Antonio, Soler, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Clinical Guides in Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986666/
https://www.ncbi.nlm.nih.gov/pubmed/35320504
http://dx.doi.org/10.1007/s12094-022-02806-x
Descripción
Sumario:Cancer of unknown primary site (CUP) is defined as a heterogeneous group of tumors that appear as metastases, and of which standard diagnostic work-up fails to identify the origin. It is considered a separate entity with a specific biology, and nowadays molecular characteristics and the determination of actionable mutations may be important in a significant group of patients. In this guide, we summarize the diagnostic, therapeutic, and possible new developments in molecular medicine that may help us in the management of this unique disease entity.

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