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Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany

BACKGROUND: Obesity in the recipient is linked to inferior transplant outcome. Consequently, access to kidney transplantation (KT) is often restricted by body mass index (BMI) thresholds. Bariatric surgery (BS) has been established as a superior treatment for obesity compared to conservative measure...

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Autores principales: Dziodzio, Tomasz, Hillebrandt, Karl Herbert, Knitter, Sebastian, Nösser, Maximilian, Globke, Brigitta, Ritschl, Paul Viktor, Biebl, Matthias, Denecke, Christian, Raakow, Jonas, Lurje, Georg, Schöning, Wenzel, Schmelzle, Moritz, Kahl, Andreas, Fütterer, Markus, Budde, Klemens, Eckardt, Kai-Uwe, Halleck, Fabian, Pratschke, Johann, Öllinger, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986752/
https://www.ncbi.nlm.nih.gov/pubmed/35305229
http://dx.doi.org/10.1007/s11695-022-06000-4
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author Dziodzio, Tomasz
Hillebrandt, Karl Herbert
Knitter, Sebastian
Nösser, Maximilian
Globke, Brigitta
Ritschl, Paul Viktor
Biebl, Matthias
Denecke, Christian
Raakow, Jonas
Lurje, Georg
Schöning, Wenzel
Schmelzle, Moritz
Kahl, Andreas
Fütterer, Markus
Budde, Klemens
Eckardt, Kai-Uwe
Halleck, Fabian
Pratschke, Johann
Öllinger, Robert
author_facet Dziodzio, Tomasz
Hillebrandt, Karl Herbert
Knitter, Sebastian
Nösser, Maximilian
Globke, Brigitta
Ritschl, Paul Viktor
Biebl, Matthias
Denecke, Christian
Raakow, Jonas
Lurje, Georg
Schöning, Wenzel
Schmelzle, Moritz
Kahl, Andreas
Fütterer, Markus
Budde, Klemens
Eckardt, Kai-Uwe
Halleck, Fabian
Pratschke, Johann
Öllinger, Robert
author_sort Dziodzio, Tomasz
collection PubMed
description BACKGROUND: Obesity in the recipient is linked to inferior transplant outcome. Consequently, access to kidney transplantation (KT) is often restricted by body mass index (BMI) thresholds. Bariatric surgery (BS) has been established as a superior treatment for obesity compared to conservative measures, but it is unclear whether it is beneficial for patients on the waiting list. METHODS: A national survey consisting of 16 questions was sent to all heads of German KT centers. Current situation of KT candidates with obesity and the status of BS were queried. RESULTS: Center response rate was 100%. Obesity in KT candidates was considered an important issue (96.1%; n = 49/51) and 68.6% (n = 35/51) of departments responded to use absolute BMI thresholds for KT waiting list access with ≥ 35 kg/m(2) (45.1%; n = 23/51) as the most common threshold. BS was considered an appropriate weight loss therapy (92.2%; n = 47/51), in particular before KT (88.2%; n = 45/51). Sleeve gastrectomy was the most favored procedure (77.1%; n = 37/51). Twenty-one (41.2%) departments responded to evaluate KT candidates with obesity by default but only 11 (21.6%) had experience with ≥ n = 5 transplants after BS. Concerns against BS were malabsorption of immunosuppressive therapy (39.2%; n = 20/51), perioperative morbidity (17.6%; n = 9/51), and malnutrition (13.7%; n = 7/51). CONCLUSIONS: Obesity is potentially limiting access for KT. Despite commonly used BMI limits, only few German centers consider BS for obesity treatment in KT candidates by default. A national multicenter study is desired by nearly all heads of German transplant centers to prospectively assess the potentials, risks, and safety of BS in KT waitlisted patients. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11695-022-06000-4.
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spelling pubmed-89867522022-04-22 Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany Dziodzio, Tomasz Hillebrandt, Karl Herbert Knitter, Sebastian Nösser, Maximilian Globke, Brigitta Ritschl, Paul Viktor Biebl, Matthias Denecke, Christian Raakow, Jonas Lurje, Georg Schöning, Wenzel Schmelzle, Moritz Kahl, Andreas Fütterer, Markus Budde, Klemens Eckardt, Kai-Uwe Halleck, Fabian Pratschke, Johann Öllinger, Robert Obes Surg Original Contributions BACKGROUND: Obesity in the recipient is linked to inferior transplant outcome. Consequently, access to kidney transplantation (KT) is often restricted by body mass index (BMI) thresholds. Bariatric surgery (BS) has been established as a superior treatment for obesity compared to conservative measures, but it is unclear whether it is beneficial for patients on the waiting list. METHODS: A national survey consisting of 16 questions was sent to all heads of German KT centers. Current situation of KT candidates with obesity and the status of BS were queried. RESULTS: Center response rate was 100%. Obesity in KT candidates was considered an important issue (96.1%; n = 49/51) and 68.6% (n = 35/51) of departments responded to use absolute BMI thresholds for KT waiting list access with ≥ 35 kg/m(2) (45.1%; n = 23/51) as the most common threshold. BS was considered an appropriate weight loss therapy (92.2%; n = 47/51), in particular before KT (88.2%; n = 45/51). Sleeve gastrectomy was the most favored procedure (77.1%; n = 37/51). Twenty-one (41.2%) departments responded to evaluate KT candidates with obesity by default but only 11 (21.6%) had experience with ≥ n = 5 transplants after BS. Concerns against BS were malabsorption of immunosuppressive therapy (39.2%; n = 20/51), perioperative morbidity (17.6%; n = 9/51), and malnutrition (13.7%; n = 7/51). CONCLUSIONS: Obesity is potentially limiting access for KT. Despite commonly used BMI limits, only few German centers consider BS for obesity treatment in KT candidates by default. A national multicenter study is desired by nearly all heads of German transplant centers to prospectively assess the potentials, risks, and safety of BS in KT waitlisted patients. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11695-022-06000-4. Springer US 2022-03-19 2022 /pmc/articles/PMC8986752/ /pubmed/35305229 http://dx.doi.org/10.1007/s11695-022-06000-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Contributions
Dziodzio, Tomasz
Hillebrandt, Karl Herbert
Knitter, Sebastian
Nösser, Maximilian
Globke, Brigitta
Ritschl, Paul Viktor
Biebl, Matthias
Denecke, Christian
Raakow, Jonas
Lurje, Georg
Schöning, Wenzel
Schmelzle, Moritz
Kahl, Andreas
Fütterer, Markus
Budde, Klemens
Eckardt, Kai-Uwe
Halleck, Fabian
Pratschke, Johann
Öllinger, Robert
Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany
title Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany
title_full Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany
title_fullStr Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany
title_full_unstemmed Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany
title_short Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany
title_sort body mass index thresholds and the use of bariatric surgery in the field of kidney transplantation in germany
topic Original Contributions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986752/
https://www.ncbi.nlm.nih.gov/pubmed/35305229
http://dx.doi.org/10.1007/s11695-022-06000-4
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