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DELE1 tracks perturbed protein import and processing in human mitochondria

Protein homeostatic control of mitochondria is key to age-related diseases and organismal decline. However, it is unknown how the diverse types of stress experienced by mitochondria can be integrated and appropriately responded to in human cells. Here we identify perturbations in the ancient conserv...

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Detalles Bibliográficos
Autores principales: Fessler, Evelyn, Krumwiede, Luisa, Jae, Lucas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986780/
https://www.ncbi.nlm.nih.gov/pubmed/35388015
http://dx.doi.org/10.1038/s41467-022-29479-y

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