STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming

The cohesin complex participates in the organization of 3D genome through generating and maintaining DNA loops. Stromal antigen 2 (STAG2), a core subunit of the cohesin complex, is frequently mutated in various cancers. However, the impact of STAG2 inactivation on 3D genome organization, especially...

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Detalles Bibliográficos
Autores principales: Chu, Zhaowei, Gu, Lei, Hu, Yeguang, Zhang, Xiaoyang, Li, Man, Chen, Jiajia, Teng, Da, Huang, Man, Shen, Che-Hung, Cai, Li, Yoshida, Toshimi, Qi, Yifeng, Niu, Zhixin, Feng, Austin, Geng, Songmei, Frederick, Dennie T., Specht, Emma, Piris, Adriano, Sullivan, Ryan J., Flaherty, Keith T., Boland, Genevieve M., Georgopoulos, Katia, Liu, David, Shi, Yang, Zheng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986786/
https://www.ncbi.nlm.nih.gov/pubmed/35388001
http://dx.doi.org/10.1038/s41467-022-29541-9

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