TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis

Tumor necrosis factor-α-induced protein 8 (TNFAIP8 or TIPE) is a member of the TNFAIP8 family. While TIPE was broadly considered to be pro-cancerous, its precise roles in carcinogenesis especially those of the intestinal tract are not clear. Here, we show that genetic deletion of TIPE in mice exacer...

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Detalles Bibliográficos
Autores principales: Lou, Yunwei, Tian, Xueqin, Sun, Chen, Song, Miaomiao, Han, Meijuan, Zhao, Yuxin, Song, Yaru, Song, Xiangfeng, Zhang, Wen, Chen, Youhai H., Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986800/
https://www.ncbi.nlm.nih.gov/pubmed/35387985
http://dx.doi.org/10.1038/s41419-022-04769-x

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