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A register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of PAPSIGOT)

The objective was to investigate if pre-stroke physical activity is associated with intact cognition early after stroke. The study design was a cross-sectional, register-based study. The study sample included 1111 adults with first stroke (mild or moderate severity) admitted to three Swedish stroke...

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Autores principales: Reinholdsson, Malin, Abzhandadze, Tamar, Palstam, Annie, Sunnerhagen, Katharina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986803/
https://www.ncbi.nlm.nih.gov/pubmed/35388045
http://dx.doi.org/10.1038/s41598-022-09520-2
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author Reinholdsson, Malin
Abzhandadze, Tamar
Palstam, Annie
Sunnerhagen, Katharina S.
author_facet Reinholdsson, Malin
Abzhandadze, Tamar
Palstam, Annie
Sunnerhagen, Katharina S.
author_sort Reinholdsson, Malin
collection PubMed
description The objective was to investigate if pre-stroke physical activity is associated with intact cognition early after stroke. The study design was a cross-sectional, register-based study. The study sample included 1111 adults with first stroke (mild or moderate severity) admitted to three Swedish stroke units. The main outcome was cognition. The associations of pre-stroke physical activity, age, sex, smoking, diabetes, atrial fibrillation, previous TIA, statin treatment, hypertension treatment, reperfusion therapies, stroke severity, and education on the outcome cognition were analyzed using binary logistic regression. Physical activity was assessed within 48 h of admittance, and cognition was screened during stroke unit care. The results were: mean age 70 years, 40% women, 61% pre-stroke physically active, and 53% with post-stroke cognitive impairment. Patients with pre-stroke light or moderate physical activity have higher odds for intact cognition compared to inactive: odds ratio (95% confidence interval) 1.32 (0.97-1.80) and 2.04 (1.18-3.53), respectively. In addition to pre-stroke physical activity, people with younger age, a higher level of education, less severe stroke (more mild than moderate), being non-diabetic, and non-smoking have higher odds for intact cognition. In conclusion physical activity before stroke is associated with intact cognition in patients with mild and moderate stroke.
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spelling pubmed-89868032022-04-08 A register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of PAPSIGOT) Reinholdsson, Malin Abzhandadze, Tamar Palstam, Annie Sunnerhagen, Katharina S. Sci Rep Article The objective was to investigate if pre-stroke physical activity is associated with intact cognition early after stroke. The study design was a cross-sectional, register-based study. The study sample included 1111 adults with first stroke (mild or moderate severity) admitted to three Swedish stroke units. The main outcome was cognition. The associations of pre-stroke physical activity, age, sex, smoking, diabetes, atrial fibrillation, previous TIA, statin treatment, hypertension treatment, reperfusion therapies, stroke severity, and education on the outcome cognition were analyzed using binary logistic regression. Physical activity was assessed within 48 h of admittance, and cognition was screened during stroke unit care. The results were: mean age 70 years, 40% women, 61% pre-stroke physically active, and 53% with post-stroke cognitive impairment. Patients with pre-stroke light or moderate physical activity have higher odds for intact cognition compared to inactive: odds ratio (95% confidence interval) 1.32 (0.97-1.80) and 2.04 (1.18-3.53), respectively. In addition to pre-stroke physical activity, people with younger age, a higher level of education, less severe stroke (more mild than moderate), being non-diabetic, and non-smoking have higher odds for intact cognition. In conclusion physical activity before stroke is associated with intact cognition in patients with mild and moderate stroke. Nature Publishing Group UK 2022-04-06 /pmc/articles/PMC8986803/ /pubmed/35388045 http://dx.doi.org/10.1038/s41598-022-09520-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Reinholdsson, Malin
Abzhandadze, Tamar
Palstam, Annie
Sunnerhagen, Katharina S.
A register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of PAPSIGOT)
title A register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of PAPSIGOT)
title_full A register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of PAPSIGOT)
title_fullStr A register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of PAPSIGOT)
title_full_unstemmed A register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of PAPSIGOT)
title_short A register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of PAPSIGOT)
title_sort register-based study on associations between pre-stroke physical activity and cognition early after stroke (part of papsigot)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986803/
https://www.ncbi.nlm.nih.gov/pubmed/35388045
http://dx.doi.org/10.1038/s41598-022-09520-2
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