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Architecture of the human NALCN channelosome
NALCN regulates the resting membrane potential by mediating the Na(+) leak current in neurons, and it functions as a channelosome in complex with FAM155A, UNC79, and UNC80. Dysfunction of the NALCN channelosome causes a broad range of neurological and developmental diseases called NALCN channelopath...
Autores principales: | Zhou, Lunni, Liu, Haobin, Zhao, Qingqing, Wu, Jianping, Yan, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986805/ https://www.ncbi.nlm.nih.gov/pubmed/35387979 http://dx.doi.org/10.1038/s41421-022-00392-4 |
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