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Targeting nicotinamide N-methyltransferase overcomes resistance to EGFR-TKI in non-small cell lung cancer cells

Activating mutations of epidermal growth factor receptor (EGFR) contributes to the progression of non-small cell lung cancer (NSCLC). EGFR tyrosine kinase inhibitor (TKI)-targeted therapy has become the standard treatment for NSCLC patients with EGFR-mutations. However, acquired resistance to these...

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Detalles Bibliográficos
Autores principales:	Wang, Jun, Liu, Xi, Huang, Yuanfeng, Li, Pan, Yang, Minqiang, Zeng, Shanshan, Chen, Danyang, Wang, Qian, Liu, Hao, Luo, Kai, Deng, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986855/ https://www.ncbi.nlm.nih.gov/pubmed/35387964 http://dx.doi.org/10.1038/s41420-022-00966-x

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