Cargando…

SARS-CoV-2 Seroprevalence Among Health Care Workers in Major Private and Public Hospitals With COVID-19 Patient's Referral in Tehran, Iran

Estimating the prevalence of SARS-CoV-2 antibody seropositivity among health care workers (HCWs) is crucial. In this study, the seroprevalence of anti-SARS-CoV-2 antibodies among HCWs of five hospitals of Tehran, Iran with high COVID-19 patient's referrals from April to June, 2020, was assessed...

Descripción completa

Detalles Bibliográficos
Autores principales: Darvishian, Maryam, Sharafkhah, Maryam, Mohammadi, Zahra, Sadeghniiat-haghighi, Khosro, Abdollahi, Alireza, Jafary, Mohamadreza, Talaschian, Mona, Tabarsi, Payam, Baghai, Parvaneh, Mardani, Masoud, Shayanrad, Amaneh, Shafighian, Fatemeh, Markarian, Melineh, Roozafzai, Farzin, Zamani, Mohammad, Alvand, Saba, Hariri, Sanam, Sadeghi, Anahita, Poustchi, Hossein, Malekzadeh, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987007/
https://www.ncbi.nlm.nih.gov/pubmed/35400056
http://dx.doi.org/10.3389/fpubh.2022.832003
_version_ 1784682642069782528
author Darvishian, Maryam
Sharafkhah, Maryam
Mohammadi, Zahra
Sadeghniiat-haghighi, Khosro
Abdollahi, Alireza
Jafary, Mohamadreza
Talaschian, Mona
Tabarsi, Payam
Baghai, Parvaneh
Mardani, Masoud
Shayanrad, Amaneh
Shafighian, Fatemeh
Markarian, Melineh
Roozafzai, Farzin
Zamani, Mohammad
Alvand, Saba
Hariri, Sanam
Sadeghi, Anahita
Poustchi, Hossein
Malekzadeh, Reza
author_facet Darvishian, Maryam
Sharafkhah, Maryam
Mohammadi, Zahra
Sadeghniiat-haghighi, Khosro
Abdollahi, Alireza
Jafary, Mohamadreza
Talaschian, Mona
Tabarsi, Payam
Baghai, Parvaneh
Mardani, Masoud
Shayanrad, Amaneh
Shafighian, Fatemeh
Markarian, Melineh
Roozafzai, Farzin
Zamani, Mohammad
Alvand, Saba
Hariri, Sanam
Sadeghi, Anahita
Poustchi, Hossein
Malekzadeh, Reza
author_sort Darvishian, Maryam
collection PubMed
description Estimating the prevalence of SARS-CoV-2 antibody seropositivity among health care workers (HCWs) is crucial. In this study, the seroprevalence of anti-SARS-CoV-2 antibodies among HCWs of five hospitals of Tehran, Iran with high COVID-19 patient's referrals from April to June, 2020, was assessed. In this cross-sectional study, HCWs from three public and two private hospitals, selected randomly as a pilot, were included. Participants were asked questions on their demographic characteristics, medical history, hospital role, and usage of personal protective equipment (PPE). Iran FDA-approved SARS-CoV-2 ELISA kits were used to detect IgG and IgM antibodies in blood samples. The seroprevalence was estimated on the basis of ELISA test results and adjusted for test performance. Among the 2,065 participants, 1,825 (88.4%) and 240 (11.6%) HCWs were recruited from public and private hospitals, respectively. A total of 340 HCWs were tested positive for SARS-CoV-2-specific IgG or IgM antibodies, and 17.9% of seropositive individuals were asymptomatic. The overall test performance-adjusted seroprevalence estimate among HCWs was 22.6 (95% CI: 20.2–25.1), and PPE usage was significantly higher among HCWs of public vs. private hospitals (66.5 vs. 20.0%). This study found that seroprevalence of SARS-CoV-2 among HCWs was higher in private hospitals (37.0%; 95% CI: 28.6–46.2) than public hospitals (20.7%; 95% CI: 18.2–23.3), and also highest among assistant nurses and nurses, and lowest among janitor or superintendent categories. The PPE usage was especially suboptimal among HCWs in private hospitals. Continued effort in access to adequate PPE and regular screening of hospital staff for detecting asymptomatic personnel, especially during the upcoming wave of infection, are warranted.
format Online
Article
Text
id pubmed-8987007
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-89870072022-04-08 SARS-CoV-2 Seroprevalence Among Health Care Workers in Major Private and Public Hospitals With COVID-19 Patient's Referral in Tehran, Iran Darvishian, Maryam Sharafkhah, Maryam Mohammadi, Zahra Sadeghniiat-haghighi, Khosro Abdollahi, Alireza Jafary, Mohamadreza Talaschian, Mona Tabarsi, Payam Baghai, Parvaneh Mardani, Masoud Shayanrad, Amaneh Shafighian, Fatemeh Markarian, Melineh Roozafzai, Farzin Zamani, Mohammad Alvand, Saba Hariri, Sanam Sadeghi, Anahita Poustchi, Hossein Malekzadeh, Reza Front Public Health Public Health Estimating the prevalence of SARS-CoV-2 antibody seropositivity among health care workers (HCWs) is crucial. In this study, the seroprevalence of anti-SARS-CoV-2 antibodies among HCWs of five hospitals of Tehran, Iran with high COVID-19 patient's referrals from April to June, 2020, was assessed. In this cross-sectional study, HCWs from three public and two private hospitals, selected randomly as a pilot, were included. Participants were asked questions on their demographic characteristics, medical history, hospital role, and usage of personal protective equipment (PPE). Iran FDA-approved SARS-CoV-2 ELISA kits were used to detect IgG and IgM antibodies in blood samples. The seroprevalence was estimated on the basis of ELISA test results and adjusted for test performance. Among the 2,065 participants, 1,825 (88.4%) and 240 (11.6%) HCWs were recruited from public and private hospitals, respectively. A total of 340 HCWs were tested positive for SARS-CoV-2-specific IgG or IgM antibodies, and 17.9% of seropositive individuals were asymptomatic. The overall test performance-adjusted seroprevalence estimate among HCWs was 22.6 (95% CI: 20.2–25.1), and PPE usage was significantly higher among HCWs of public vs. private hospitals (66.5 vs. 20.0%). This study found that seroprevalence of SARS-CoV-2 among HCWs was higher in private hospitals (37.0%; 95% CI: 28.6–46.2) than public hospitals (20.7%; 95% CI: 18.2–23.3), and also highest among assistant nurses and nurses, and lowest among janitor or superintendent categories. The PPE usage was especially suboptimal among HCWs in private hospitals. Continued effort in access to adequate PPE and regular screening of hospital staff for detecting asymptomatic personnel, especially during the upcoming wave of infection, are warranted. Frontiers Media S.A. 2022-03-24 /pmc/articles/PMC8987007/ /pubmed/35400056 http://dx.doi.org/10.3389/fpubh.2022.832003 Text en Copyright © 2022 Darvishian, Sharafkhah, Mohammadi, Sadeghniiat-haghighi, Abdollahi, Jafary, Talaschian, Tabarsi, Baghai, Mardani, Shayanrad, Shafighian, Markarian, Roozafzai, Zamani, Alvand, Hariri, Sadeghi, Poustchi and Malekzadeh. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Darvishian, Maryam
Sharafkhah, Maryam
Mohammadi, Zahra
Sadeghniiat-haghighi, Khosro
Abdollahi, Alireza
Jafary, Mohamadreza
Talaschian, Mona
Tabarsi, Payam
Baghai, Parvaneh
Mardani, Masoud
Shayanrad, Amaneh
Shafighian, Fatemeh
Markarian, Melineh
Roozafzai, Farzin
Zamani, Mohammad
Alvand, Saba
Hariri, Sanam
Sadeghi, Anahita
Poustchi, Hossein
Malekzadeh, Reza
SARS-CoV-2 Seroprevalence Among Health Care Workers in Major Private and Public Hospitals With COVID-19 Patient's Referral in Tehran, Iran
title SARS-CoV-2 Seroprevalence Among Health Care Workers in Major Private and Public Hospitals With COVID-19 Patient's Referral in Tehran, Iran
title_full SARS-CoV-2 Seroprevalence Among Health Care Workers in Major Private and Public Hospitals With COVID-19 Patient's Referral in Tehran, Iran
title_fullStr SARS-CoV-2 Seroprevalence Among Health Care Workers in Major Private and Public Hospitals With COVID-19 Patient's Referral in Tehran, Iran
title_full_unstemmed SARS-CoV-2 Seroprevalence Among Health Care Workers in Major Private and Public Hospitals With COVID-19 Patient's Referral in Tehran, Iran
title_short SARS-CoV-2 Seroprevalence Among Health Care Workers in Major Private and Public Hospitals With COVID-19 Patient's Referral in Tehran, Iran
title_sort sars-cov-2 seroprevalence among health care workers in major private and public hospitals with covid-19 patient's referral in tehran, iran
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987007/
https://www.ncbi.nlm.nih.gov/pubmed/35400056
http://dx.doi.org/10.3389/fpubh.2022.832003
work_keys_str_mv AT darvishianmaryam sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT sharafkhahmaryam sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT mohammadizahra sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT sadeghniiathaghighikhosro sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT abdollahialireza sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT jafarymohamadreza sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT talaschianmona sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT tabarsipayam sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT baghaiparvaneh sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT mardanimasoud sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT shayanradamaneh sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT shafighianfatemeh sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT markarianmelineh sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT roozafzaifarzin sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT zamanimohammad sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT alvandsaba sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT haririsanam sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT sadeghianahita sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT poustchihossein sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran
AT malekzadehreza sarscov2seroprevalenceamonghealthcareworkersinmajorprivateandpublichospitalswithcovid19patientsreferralintehraniran