Metal-responsive regulation of enzyme catalysis using genetically encoded chemical switches

Dynamic control over protein function is a central challenge in synthetic biology. To address this challenge, we describe the development of an integrated computational and experimental workflow to incorporate a metal-responsive chemical switch into proteins. Pairs of bipyridinylalanine (BpyAla) res...

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Detalles Bibliográficos
Autores principales: Zubi, Yasmine S., Seki, Kosuke, Li, Ying, Hunt, Andrew C., Liu, Bingqing, Roux, Benoît, Jewett, Michael C., Lewis, Jared C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987029/
https://www.ncbi.nlm.nih.gov/pubmed/35387988
http://dx.doi.org/10.1038/s41467-022-29239-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987029/
https://www.ncbi.nlm.nih.gov/pubmed/35387988
http://dx.doi.org/10.1038/s41467-022-29239-y

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