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Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard

Species distributed across climatic gradients will typically experience spatial variation in selection, but gene flow can prevent such selection from causing population genetic differentiation and local adaptation. Here, we studied genomic variation of 415 individuals across 34 populations of the co...

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Autores principales: Ruiz Miñano, Maravillas, While, Geoffrey M., Yang, Weizhao, Burridge, Christopher P., Salvi, Daniele, Uller, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987050/
https://www.ncbi.nlm.nih.gov/pubmed/35277668
http://dx.doi.org/10.1038/s41437-022-00518-0
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author Ruiz Miñano, Maravillas
While, Geoffrey M.
Yang, Weizhao
Burridge, Christopher P.
Salvi, Daniele
Uller, Tobias
author_facet Ruiz Miñano, Maravillas
While, Geoffrey M.
Yang, Weizhao
Burridge, Christopher P.
Salvi, Daniele
Uller, Tobias
author_sort Ruiz Miñano, Maravillas
collection PubMed
description Species distributed across climatic gradients will typically experience spatial variation in selection, but gene flow can prevent such selection from causing population genetic differentiation and local adaptation. Here, we studied genomic variation of 415 individuals across 34 populations of the common wall lizard (Podarcis muralis) in central Italy. This species is highly abundant throughout this region and populations belong to a single genetic lineage, yet there is extensive phenotypic variation across climatic regimes. We used redundancy analysis to, first, quantify the effect of climate and geography on population genomic variation in this region and, second, to test if climate consistently sorts specific alleles across the landscape. Climate explained 5% of the population genomic variation across the landscape, about half of which was collinear with geography. Linear models and redundancy analyses identified loci that were significantly differentiated across climatic regimes. These loci were distributed across the genome and physically associated with genes putatively involved in thermal tolerance, regulation of temperature-dependent metabolism and reproductive activity, and body colouration. Together, these findings suggest that climate can exercise sufficient selection in lizards to promote genetic differentiation across the landscape in spite of high gene flow.
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spelling pubmed-89870502022-04-22 Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard Ruiz Miñano, Maravillas While, Geoffrey M. Yang, Weizhao Burridge, Christopher P. Salvi, Daniele Uller, Tobias Heredity (Edinb) Article Species distributed across climatic gradients will typically experience spatial variation in selection, but gene flow can prevent such selection from causing population genetic differentiation and local adaptation. Here, we studied genomic variation of 415 individuals across 34 populations of the common wall lizard (Podarcis muralis) in central Italy. This species is highly abundant throughout this region and populations belong to a single genetic lineage, yet there is extensive phenotypic variation across climatic regimes. We used redundancy analysis to, first, quantify the effect of climate and geography on population genomic variation in this region and, second, to test if climate consistently sorts specific alleles across the landscape. Climate explained 5% of the population genomic variation across the landscape, about half of which was collinear with geography. Linear models and redundancy analyses identified loci that were significantly differentiated across climatic regimes. These loci were distributed across the genome and physically associated with genes putatively involved in thermal tolerance, regulation of temperature-dependent metabolism and reproductive activity, and body colouration. Together, these findings suggest that climate can exercise sufficient selection in lizards to promote genetic differentiation across the landscape in spite of high gene flow. Springer International Publishing 2022-03-11 2022-04 /pmc/articles/PMC8987050/ /pubmed/35277668 http://dx.doi.org/10.1038/s41437-022-00518-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ruiz Miñano, Maravillas
While, Geoffrey M.
Yang, Weizhao
Burridge, Christopher P.
Salvi, Daniele
Uller, Tobias
Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard
title Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard
title_full Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard
title_fullStr Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard
title_full_unstemmed Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard
title_short Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard
title_sort population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987050/
https://www.ncbi.nlm.nih.gov/pubmed/35277668
http://dx.doi.org/10.1038/s41437-022-00518-0
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