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Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics

PoxtA and OptrA are ATP binding cassette (ABC) proteins of the F subtype (ABCF). They confer resistance to oxazolidinone and phenicol antibiotics, such as linezolid and chloramphenicol, which stall translating ribosomes when certain amino acids are present at a defined position in the nascent polype...

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Detalles Bibliográficos
Autores principales:	Crowe-McAuliffe, Caillan, Murina, Victoriia, Turnbull, Kathryn Jane, Huch, Susanne, Kasari, Marje, Takada, Hiraku, Nersisyan, Lilit, Sundsfjord, Arnfinn, Hegstad, Kristin, Atkinson, Gemma C., Pelechano, Vicent, Wilson, Daniel N., Hauryliuk, Vasili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987054/ https://www.ncbi.nlm.nih.gov/pubmed/35387982 http://dx.doi.org/10.1038/s41467-022-29274-9

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