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Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment

Immunosuppressive cells residing in the tumor microenvironment, especially tumor associated macrophages (TAMs), hinder the infiltration and activation of T cells, limiting the anti-cancer outcomes of immune checkpoint blockade. Here, we report a biocompatible alginate-based hydrogel loaded with Pexi...

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Detalles Bibliográficos
Autores principales:	Li, Zhaoting, Ding, Yingyue, Liu, Jun, Wang, Jianxin, Mo, Fanyi, Wang, Yixin, Chen-Mayfield, Ting-Jing, Sondel, Paul M., Hong, Seungpyo, Hu, Quanyin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987059/ https://www.ncbi.nlm.nih.gov/pubmed/35387972 http://dx.doi.org/10.1038/s41467-022-29388-0

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