Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis

Sensing of pathogens by pattern recognition receptors (PRR) is critical to initiate protective host defence reactions. However, activation of the immune system has to be carefully titrated to avoid tissue damage necessitating mechanisms to control and terminate PRR signalling. Dectin-1 is a PRR for...

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Detalles Bibliográficos
Autores principales: Mentrup, Torben, Stumpff-Niggemann, Anna Yamina, Leinung, Nadja, Schlosser, Christine, Schubert, Katja, Wehner, Rebekka, Tunger, Antje, Schatz, Valentin, Neubert, Patrick, Gradtke, Ann-Christine, Wolf, Janina, Rose-John, Stefan, Saftig, Paul, Dalpke, Alexander, Jantsch, Jonathan, Schmitz, Marc, Fluhrer, Regina, Jacobsen, Ilse D., Schröder, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987071/
https://www.ncbi.nlm.nih.gov/pubmed/35388002
http://dx.doi.org/10.1038/s41467-022-29474-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987071/
https://www.ncbi.nlm.nih.gov/pubmed/35388002
http://dx.doi.org/10.1038/s41467-022-29474-3

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