Cargando…

Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis

Sensing of pathogens by pattern recognition receptors (PRR) is critical to initiate protective host defence reactions. However, activation of the immune system has to be carefully titrated to avoid tissue damage necessitating mechanisms to control and terminate PRR signalling. Dectin-1 is a PRR for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mentrup, Torben, Stumpff-Niggemann, Anna Yamina, Leinung, Nadja, Schlosser, Christine, Schubert, Katja, Wehner, Rebekka, Tunger, Antje, Schatz, Valentin, Neubert, Patrick, Gradtke, Ann-Christine, Wolf, Janina, Rose-John, Stefan, Saftig, Paul, Dalpke, Alexander, Jantsch, Jonathan, Schmitz, Marc, Fluhrer, Regina, Jacobsen, Ilse D., Schröder, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987071/ https://www.ncbi.nlm.nih.gov/pubmed/35388002 http://dx.doi.org/10.1038/s41467-022-29474-3

Ejemplares similares

Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis
por: Mentrup, Torben, et al.
Publicado: (2019)

Physiological functions of SPP/SPPL intramembrane proteases
por: Mentrup, Torben, et al.
Publicado: (2020)

Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
por: Leinung, Nadja, et al.
Publicado: (2023)

Covalent fragment inhibits intramembrane proteolysis
por: Eden, Angela, et al.
Publicado: (2022)

Signaling Functions of Intramembrane Aspartyl-Proteases
por: Papadopoulou, Alkmini A., et al.
Publicado: (2020)

Intramembrane proteases protect from atherosclerosis
por: Mentrup, Torben, et al.
Publicado: (2019)

Intramembrane cleaving proteases (I-CLiPs) as guardians of shuttling proteins
por: Fluhrer, Regina
Publicado: (2014)

Substrate–Enzyme Interactions in Intramembrane Proteolysis: γ-Secretase as the Prototype
por: Liu, Xinyue, et al.
Publicado: (2020)

Heme binding of transmembrane signaling proteins undergoing regulated intramembrane proteolysis
por: Kupke, Thomas, et al.
Publicado: (2020)

Bacterial SEAL domains undergo autoproteolysis and function in regulated intramembrane proteolysis
por: Brogan, Anna P., et al.
Publicado: (2023)

The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain
por: Schneppenheim, Janna, et al.
Publicado: (2013)

Sequence-Specific Intramembrane Proteolysis: Identification of a Recognition Motif in Rhomboid Substrates
por: Strisovsky, Kvido, et al.
Publicado: (2009)

QARIP: a web server for quantitative proteomic analysis of regulated intramembrane proteolysis
por: Ivankov, Dmitry N., et al.
Publicado: (2013)

Rhomboid-catalyzed intramembrane proteolysis requires hydrophobic matching with the surrounding lipid bilayer
por: Engberg, Oskar, et al.
Publicado: (2022)

The transmembrane domain of Frey1 harbors a transplantable inhibitory motif for intramembrane proteases
por: Contreras, Whendy, et al.
Publicado: (2023)

Ligand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3
por: Degnin, Catherine R., et al.
Publicado: (2011)

The Coxsackievirus and Adenovirus Receptor (CAR) Undergoes Ectodomain Shedding and Regulated Intramembrane Proteolysis (RIP)
por: Houri, Nadia, et al.
Publicado: (2013)

Coupled Transmembrane Substrate Docking and Helical Unwinding in Intramembrane Proteolysis of Amyloid Precursor Protein
por: Clemente, Nicolina, et al.
Publicado: (2018)

Evidence that regulation of intramembrane proteolysis is mediated by substrate gating during sporulation in Bacillus subtilis
por: Ramírez-Guadiana, Fernando H., et al.
Publicado: (2018)

Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release
por: Cho, Sangwoo, et al.
Publicado: (2019)

Sodium channel β1 subunits participate in regulated intramembrane proteolysis-excitation coupling
por: Bouza, Alexandra A., et al.
Publicado: (2021)

Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite
por: O'Donnell, Rebecca A., et al.
Publicado: (2006)

Regulated Intramembrane Proteolysis and Degradation of Murine Epithelial Cell Adhesion Molecule mEpCAM
por: Hachmeister, Matthias, et al.
Publicado: (2013)

MBTPS2 mutations cause defective regulated intramembrane proteolysis in X-linked osteogenesis imperfecta
por: Lindert, Uschi, et al.
Publicado: (2016)

Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy
por: Wu, Bo, et al.
Publicado: (2017)

Regulated Intramembrane Proteolysis of ACE2: A Potential Mechanism Contributing to COVID-19 Pathogenesis?
por: Gonzalez, Sandra M., et al.
Publicado: (2021)

Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP
por: Imaizumi, Yuki, et al.
Publicado: (2022)

Active site geometry stabilization of a presenilin homolog by the lipid bilayer promotes intramembrane proteolysis
por: Feilen, Lukas P, et al.
Publicado: (2022)

Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase
por: Werner, Nadine T., et al.
Publicado: (2023)

Bi-functional particles for real-time phagosome acidification and proteolysis multiplex assay in macrophages
por: Méndez-Alejandre, Alba, et al.
Publicado: (2023)

Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis
por: Chen, Allen C., et al.
Publicado: (2015)

Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells
por: Lu, Yinzhong, et al.
Publicado: (2017)

Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function
por: Cho, Youngkyung, et al.
Publicado: (2020)

Sustained Induction of Collagen Synthesis by TGF-β Requires Regulated Intramembrane Proteolysis of CREB3L1
por: Chen, Qiuyue, et al.
Publicado: (2014)

Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis
por: Koistinen, Niina A., et al.
Publicado: (2017)

Yeast‐based reporter assay system for identifying the requirements of intramembrane proteolysis by signal peptide peptidase of Arabidopsis thaliana
por: Kusunoki, Kenta, et al.
Publicado: (2020)

CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis
por: Salao, Kanin, et al.
Publicado: (2016)

The Lipid Raft-Associated Protein Stomatin Is Required for Accumulation of Dectin-1 in the Phagosomal Membrane and for Full Activity of Macrophages against Aspergillus fumigatus
por: Goldmann, Marie, et al.
Publicado: (2023)

Development of a Reporter System Monitoring Regulated Intramembrane Proteolysis of the Transmembrane bZIP Transcription Factor ATF6α
por: Kim, Jin-Ik, et al.
Publicado: (2019)

The Phagosome Proteome: Insight into Phagosome Functions
por: Garin, Jérome, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_ssc3k3fop2uh42g8rrdnjal1dm