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Elastic dosage compensation by X-chromosome upregulation

X-chromosome inactivation and X-upregulation are the fundamental modes of chromosome-wide gene regulation that collectively achieve dosage compensation in mammals, but the regulatory link between the two remains elusive and the X-upregulation dynamics are unknown. Here, we use allele-resolved single...

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Detalles Bibliográficos
Autores principales: Lentini, Antonio, Cheng, Huaitao, Noble, J. C., Papanicolaou, Natali, Coucoravas, Christos, Andrews, Nathanael, Deng, Qiaolin, Enge, Martin, Reinius, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987076/
https://www.ncbi.nlm.nih.gov/pubmed/35388014
http://dx.doi.org/10.1038/s41467-022-29414-1