Cargando…
Immunosuppressive Drugs
Immunosuppressant is a class of medicines that inhibit or decrease the intensity of the immune response in the body. Most of these medications are used to allow the body less likely to resist a transplanted organ. In solid organ transplantation, immunosuppressive agents are needed for the activation...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987166/ http://dx.doi.org/10.1016/B978-0-12-818731-9.00068-9 |
_version_ | 1784682679581540352 |
---|---|
author | Hussain, Yaseen Khan, Haroon |
author_facet | Hussain, Yaseen Khan, Haroon |
author_sort | Hussain, Yaseen |
collection | PubMed |
description | Immunosuppressant is a class of medicines that inhibit or decrease the intensity of the immune response in the body. Most of these medications are used to allow the body less likely to resist a transplanted organ. In solid organ transplantation, immunosuppressive agents are needed for the activation of early-stage immunosuppression, the management of late-stage immunosuppression or for the maintenance of organ rejection. The emergence of novel agents and improvements in immunosuppression regimens after transplantation are significant factors leading to this progress. However, these drugs also increase the risk of infection, cancers and specific adverse side effects specific to each agent in patients particularly in pregnant women and fertility issues. Corona virus disease being hot topic of debate is has given positive outcome to immunosuppressive drugs however need more attention in future. Transplant centers across the world utilize multiple immunosuppression protocols; nevertheless, each patient can require an individually formulated immunosuppression regimen to manage the advantages and possible damage of treatment thus eliminating the likelihood of their primary disease recurrence. |
format | Online Article Text |
id | pubmed-8987166 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
record_format | MEDLINE/PubMed |
spelling | pubmed-89871662022-04-07 Immunosuppressive Drugs Hussain, Yaseen Khan, Haroon Encyclopedia of Infection and Immunity Article Immunosuppressant is a class of medicines that inhibit or decrease the intensity of the immune response in the body. Most of these medications are used to allow the body less likely to resist a transplanted organ. In solid organ transplantation, immunosuppressive agents are needed for the activation of early-stage immunosuppression, the management of late-stage immunosuppression or for the maintenance of organ rejection. The emergence of novel agents and improvements in immunosuppression regimens after transplantation are significant factors leading to this progress. However, these drugs also increase the risk of infection, cancers and specific adverse side effects specific to each agent in patients particularly in pregnant women and fertility issues. Corona virus disease being hot topic of debate is has given positive outcome to immunosuppressive drugs however need more attention in future. Transplant centers across the world utilize multiple immunosuppression protocols; nevertheless, each patient can require an individually formulated immunosuppression regimen to manage the advantages and possible damage of treatment thus eliminating the likelihood of their primary disease recurrence. 2022 2022-04-08 /pmc/articles/PMC8987166/ http://dx.doi.org/10.1016/B978-0-12-818731-9.00068-9 Text en Copyright © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Hussain, Yaseen Khan, Haroon Immunosuppressive Drugs |
title | Immunosuppressive Drugs |
title_full | Immunosuppressive Drugs |
title_fullStr | Immunosuppressive Drugs |
title_full_unstemmed | Immunosuppressive Drugs |
title_short | Immunosuppressive Drugs |
title_sort | immunosuppressive drugs |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987166/ http://dx.doi.org/10.1016/B978-0-12-818731-9.00068-9 |
work_keys_str_mv | AT hussainyaseen immunosuppressivedrugs AT khanharoon immunosuppressivedrugs |