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Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung

A 71-year-old man presented with cough and bloody sputum. Computed tomography showed a mass in the lower lobe of the left lung. Histological findings in biopsy tissue revealed a malignant peripheral nerve sheath tumor (MPNST). The patient was diagnosed with primary lung MPNST based on a systemic exa...

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Detalles Bibliográficos
Autores principales: Yanagisawa, Katsuya, Nishie, Kenichi, Takahashi, Hidekazu, Sano, Kenji, Takei, Kazuyoshi, Yamamoto, Hiroshi, Koizumi, Tomonobu, Hanaoka, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987238/
https://www.ncbi.nlm.nih.gov/pubmed/35296623
http://dx.doi.org/10.2169/internalmedicine.8143-21
Descripción
Sumario:A 71-year-old man presented with cough and bloody sputum. Computed tomography showed a mass in the lower lobe of the left lung. Histological findings in biopsy tissue revealed a malignant peripheral nerve sheath tumor (MPNST). The patient was diagnosed with primary lung MPNST based on a systemic examination. Although initial chemotherapy treatment with doxorubicin failed to control the disease, radiotherapy considerably shrank the tumor. Primary lung MPNSTs are rare, and there is no established treatment for inoperable cases. This case suggests that radiotherapy is a treatment option for primary lung MPNST.