Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung

A 71-year-old man presented with cough and bloody sputum. Computed tomography showed a mass in the lower lobe of the left lung. Histological findings in biopsy tissue revealed a malignant peripheral nerve sheath tumor (MPNST). The patient was diagnosed with primary lung MPNST based on a systemic exa...

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Autores principales: Yanagisawa, Katsuya, Nishie, Kenichi, Takahashi, Hidekazu, Sano, Kenji, Takei, Kazuyoshi, Yamamoto, Hiroshi, Koizumi, Tomonobu, Hanaoka, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987238/
https://www.ncbi.nlm.nih.gov/pubmed/35296623
http://dx.doi.org/10.2169/internalmedicine.8143-21
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author Yanagisawa, Katsuya
Nishie, Kenichi
Takahashi, Hidekazu
Sano, Kenji
Takei, Kazuyoshi
Yamamoto, Hiroshi
Koizumi, Tomonobu
Hanaoka, Masayuki
author_facet Yanagisawa, Katsuya
Nishie, Kenichi
Takahashi, Hidekazu
Sano, Kenji
Takei, Kazuyoshi
Yamamoto, Hiroshi
Koizumi, Tomonobu
Hanaoka, Masayuki
author_sort Yanagisawa, Katsuya
collection PubMed
description A 71-year-old man presented with cough and bloody sputum. Computed tomography showed a mass in the lower lobe of the left lung. Histological findings in biopsy tissue revealed a malignant peripheral nerve sheath tumor (MPNST). The patient was diagnosed with primary lung MPNST based on a systemic examination. Although initial chemotherapy treatment with doxorubicin failed to control the disease, radiotherapy considerably shrank the tumor. Primary lung MPNSTs are rare, and there is no established treatment for inoperable cases. This case suggests that radiotherapy is a treatment option for primary lung MPNST.
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spelling pubmed-89872382022-04-26 Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung Yanagisawa, Katsuya Nishie, Kenichi Takahashi, Hidekazu Sano, Kenji Takei, Kazuyoshi Yamamoto, Hiroshi Koizumi, Tomonobu Hanaoka, Masayuki Intern Med Case Report A 71-year-old man presented with cough and bloody sputum. Computed tomography showed a mass in the lower lobe of the left lung. Histological findings in biopsy tissue revealed a malignant peripheral nerve sheath tumor (MPNST). The patient was diagnosed with primary lung MPNST based on a systemic examination. Although initial chemotherapy treatment with doxorubicin failed to control the disease, radiotherapy considerably shrank the tumor. Primary lung MPNSTs are rare, and there is no established treatment for inoperable cases. This case suggests that radiotherapy is a treatment option for primary lung MPNST. The Japanese Society of Internal Medicine 2022-03-15 2022-03-15 /pmc/articles/PMC8987238/ /pubmed/35296623 http://dx.doi.org/10.2169/internalmedicine.8143-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yanagisawa, Katsuya
Nishie, Kenichi
Takahashi, Hidekazu
Sano, Kenji
Takei, Kazuyoshi
Yamamoto, Hiroshi
Koizumi, Tomonobu
Hanaoka, Masayuki
Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung
title Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung
title_full Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung
title_fullStr Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung
title_full_unstemmed Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung
title_short Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung
title_sort successful radiotherapy of primary malignant peripheral nerve sheath tumor of the lung
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987238/
https://www.ncbi.nlm.nih.gov/pubmed/35296623
http://dx.doi.org/10.2169/internalmedicine.8143-21
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