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Neuronal SH2B1 attenuates apoptosis in an MPTP mouse model of Parkinson's disease via promoting PLIN4 degradation
The incidence of Parkinson's disease (PD) has increased tremendously, especially in the aged population and people with metabolic dysfunction; however, its underlying molecular mechanisms remain unclear. SH2B1, an intracellular adaptor protein, contributes to the signal transduction of several...
Autores principales: | Han, Xiaojuan, Liu, Yuan, Dai, Yan, Xu, Tianshu, Hu, Qinghui, Yi, Xiaolan, Rui, Liangyou, Hu, Gang, Hu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987406/ https://www.ncbi.nlm.nih.gov/pubmed/35390677 http://dx.doi.org/10.1016/j.redox.2022.102308 |
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