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Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis

Acute pancreatitis (AP) is an acute inflammatory disorder characterized by acinar cell death and inflammation. Multiple factors cause hyperglycemia after AP. Macrophage polarization is involved in tissue injury and repair, and is regulated by Notch signaling during certain inflammatory diseases. The...

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Detalles Bibliográficos
Autores principales: Hu, Ning, Zhang, Xiaoyi, Zhang, Xuanzhe, Guan, Yongjun, He, Ruyuan, Xue, Enfu, Deng, Wenhong, Yu, Jia, Wang, Weixing, Shi, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987789/
https://www.ncbi.nlm.nih.gov/pubmed/35302580
http://dx.doi.org/10.1042/CS20211031

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