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Vangl2 Promotes Hematopoietic Stem Cell Expansion

Regulation of hematopoietic stem cell (HSC) self-renewal and differentiation is essential for their maintenance, and HSC polarity has been shown to play an important role in this regulation. Vangl2, a key component of the Wnt/polarity pathway, is expressed by fetal and adult HSCs, but its role in he...

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Detalles Bibliográficos
Autores principales: Bouali, Sarah, Hétu-Arbour, Roxann, Gardet, Célia, Heinonen, Krista M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987925/
https://www.ncbi.nlm.nih.gov/pubmed/35399538
http://dx.doi.org/10.3389/fcell.2022.760248