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Capsaicin suppresses interleukin-31-induced itching partially involved in inhibiting the expression of dorsal root ganglion interleukin-31 receptor A in male mice

To elucidate the mechanisms underlying the antipruritic effect of capsaicin, we investigated how topical application of capsaicin (0.01, 0.1 and 1.0% w/v) affects spontaneous scratching in NC/Nga mice, inerleukin-31 (IL-31) induced in BALB/c mice, and IL-31 receptor A (IL-31RA) and transient recepto...

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Detalles Bibliográficos
Autores principales:	Arai, Iwao, Tsuji, Minoru, Takeda, Hiroshi, Akiyama, Nobutake, Saito, Saburo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988000/ https://www.ncbi.nlm.nih.gov/pubmed/35400013 http://dx.doi.org/10.1016/j.ynpai.2022.100088

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