Compartmentalization of Telomeres through DNA-scaffolded Phase Separation

Telomeres form unique nuclear compartments that prevent degradation and fusion of chromosome ends by recruiting shelterin proteins and regulating access of DNA damage repair factors. To understand how these dynamic components protect chromosome ends, we combine in vivo biophysical interrogation and...

Descripción completa

Detalles Bibliográficos
Autores principales: Jack, Amanda, Kim, Yoonji, Strom, Amy R., Lee, Daniel S.W., Williams, Byron, Schaub, Jeffrey M., Kellogg, Elizabeth H., Finkelstein, Ilya J., Ferro, Luke S., Yildiz, Ahmet, Brangwynne, Clifford P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988007/
https://www.ncbi.nlm.nih.gov/pubmed/35077681
http://dx.doi.org/10.1016/j.devcel.2021.12.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988007/
https://www.ncbi.nlm.nih.gov/pubmed/35077681
http://dx.doi.org/10.1016/j.devcel.2021.12.017

Ejemplares similares