Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Hypoxia-inducible factors (HIFs) induce numerous genes regulating oxygen homeostasis. As oxygen sensors of the cells, the HIF prolyl 4-hydroxylases (HIF-P4Hs) regulate the stability of HIFs in an oxygen-dependent manner. During hair follicle (HF) morphogenesis and cycling, the location of dermal pap...

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Detalles Bibliográficos
Autores principales: Rosendahl, Ann-Helen, Monnius, Mia, Laitala, Anu, Railo, Antti, Miinalainen, Ilkka, Heljasvaara, Ritva, Mäki, Joni M., Myllyharju, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988008/
https://www.ncbi.nlm.nih.gov/pubmed/35247391
http://dx.doi.org/10.1016/j.jbc.2022.101787

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