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The Enigma of Giant Phyllodes Tumour

Phyllodes tumours are an uncommon type of biphasic fibroepithelial neoplasm of the breast. We present a case of a 28-year-old, para one lady with no risk of breast cancer presented with painless left breast swelling for three months. Over one month, the swelling suddenly increased in size and became...

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Autores principales: Gan, Seng Yeong, Yahya, Maya Mazuwin, Wan Zain, Wan Zainira, Nik Min, Nik Fatin Amirah, Wan Abdul Rahman, Wan Faiziah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988095/
https://www.ncbi.nlm.nih.gov/pubmed/35411275
http://dx.doi.org/10.7759/cureus.22946
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author Gan, Seng Yeong
Yahya, Maya Mazuwin
Wan Zain, Wan Zainira
Nik Min, Nik Fatin Amirah
Wan Abdul Rahman, Wan Faiziah
author_facet Gan, Seng Yeong
Yahya, Maya Mazuwin
Wan Zain, Wan Zainira
Nik Min, Nik Fatin Amirah
Wan Abdul Rahman, Wan Faiziah
author_sort Gan, Seng Yeong
collection PubMed
description Phyllodes tumours are an uncommon type of biphasic fibroepithelial neoplasm of the breast. We present a case of a 28-year-old, para one lady with no risk of breast cancer presented with painless left breast swelling for three months. Over one month, the swelling suddenly increased in size and became painful with skin changes associated with pus discharge. On physical examination, a huge swelling measuring about 25cm x 30cm occupies the central and lateral aspect of the left breast with surrounding erythema. We proceeded for a tru-cut biopsy, and the histopathological examination (HPE) showed a stromal proliferation with myxoid changes consistent with phyllodes tumour of benign type. The patient underwent a left simple mastectomy, and the histopathological examination (HPE) confirmed the diagnosis of borderline phyllodes tumour with clear margins without lymph nodes involvement. The patient was subsequently referred to the oncology team and was subjected to 40 Gy in 15 fractions of radiotherapy. Given the rarity of the disease and based on current studies, simple mastectomy with negative margins is recommended for giant benign phyllodes tumours
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spelling pubmed-89880952022-04-10 The Enigma of Giant Phyllodes Tumour Gan, Seng Yeong Yahya, Maya Mazuwin Wan Zain, Wan Zainira Nik Min, Nik Fatin Amirah Wan Abdul Rahman, Wan Faiziah Cureus Pathology Phyllodes tumours are an uncommon type of biphasic fibroepithelial neoplasm of the breast. We present a case of a 28-year-old, para one lady with no risk of breast cancer presented with painless left breast swelling for three months. Over one month, the swelling suddenly increased in size and became painful with skin changes associated with pus discharge. On physical examination, a huge swelling measuring about 25cm x 30cm occupies the central and lateral aspect of the left breast with surrounding erythema. We proceeded for a tru-cut biopsy, and the histopathological examination (HPE) showed a stromal proliferation with myxoid changes consistent with phyllodes tumour of benign type. The patient underwent a left simple mastectomy, and the histopathological examination (HPE) confirmed the diagnosis of borderline phyllodes tumour with clear margins without lymph nodes involvement. The patient was subsequently referred to the oncology team and was subjected to 40 Gy in 15 fractions of radiotherapy. Given the rarity of the disease and based on current studies, simple mastectomy with negative margins is recommended for giant benign phyllodes tumours Cureus 2022-03-08 /pmc/articles/PMC8988095/ /pubmed/35411275 http://dx.doi.org/10.7759/cureus.22946 Text en Copyright © 2022, Gan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Gan, Seng Yeong
Yahya, Maya Mazuwin
Wan Zain, Wan Zainira
Nik Min, Nik Fatin Amirah
Wan Abdul Rahman, Wan Faiziah
The Enigma of Giant Phyllodes Tumour
title The Enigma of Giant Phyllodes Tumour
title_full The Enigma of Giant Phyllodes Tumour
title_fullStr The Enigma of Giant Phyllodes Tumour
title_full_unstemmed The Enigma of Giant Phyllodes Tumour
title_short The Enigma of Giant Phyllodes Tumour
title_sort enigma of giant phyllodes tumour
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988095/
https://www.ncbi.nlm.nih.gov/pubmed/35411275
http://dx.doi.org/10.7759/cureus.22946
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