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Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores

[Image: see text] The development of new analytical systems and the improvement of the existing ones to obtain high-resolution measurements of chemical markers in samples from ice cores, is one of the main challenges the paleoclimatic scientific community is facing. Different chemical species can be...

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Autores principales: Barbaro, Elena, Feltracco, Matteo, Spagnesi, Azzurra, Dallo, Federico, Gabrieli, Jacopo, De Blasi, Fabrizio, Zannoni, Daniele, Cairns, Warren R.L., Gambaro, Andrea, Barbante, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988124/
https://www.ncbi.nlm.nih.gov/pubmed/35319865
http://dx.doi.org/10.1021/acs.analchem.1c05412
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author Barbaro, Elena
Feltracco, Matteo
Spagnesi, Azzurra
Dallo, Federico
Gabrieli, Jacopo
De Blasi, Fabrizio
Zannoni, Daniele
Cairns, Warren R.L.
Gambaro, Andrea
Barbante, Carlo
author_facet Barbaro, Elena
Feltracco, Matteo
Spagnesi, Azzurra
Dallo, Federico
Gabrieli, Jacopo
De Blasi, Fabrizio
Zannoni, Daniele
Cairns, Warren R.L.
Gambaro, Andrea
Barbante, Carlo
author_sort Barbaro, Elena
collection PubMed
description [Image: see text] The development of new analytical systems and the improvement of the existing ones to obtain high-resolution measurements of chemical markers in samples from ice cores, is one of the main challenges the paleoclimatic scientific community is facing. Different chemical species can be used as markers for tracking emission sources or specific environmental processes. Although some markers, such as methane sulfonic acid (a proxy of marine productivity), are commonly used, there is a lack of data on other organic tracers in ice cores, making their continuous analysis analytically challenging. Here, we present an innovative combination of fast liquid chromatography coupled with tandem mass spectrometry (FLC-MS/MS) to continuously determine organic markers in ice cores. After specific optimization, this approach was applied to the quantification of vanillic and syringic acids, two specific markers for biomass burning. Using the validated method, detection limits of 3.6 and 4.6 pg mL(–1) for vanillic and syringic acids, respectively, were achieved. Thanks to the coupling of FLC-MS/MS with the continuous flow analytical system, we obtained one measurement every 30 s, which corresponds to a sampling resolution of a sample every 1.5 cm with a melting rate of 3.0 cm min(–1). To check the robustness of the method, we analyzed two parallel sticks of an alpine ice core over more than 5 h. Vanillic acid was found with concentrations in the range of picograms per milliliter, suggesting the combustion of coniferous trees, which are found throughout the Italian Alps.
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spelling pubmed-89881242022-04-07 Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores Barbaro, Elena Feltracco, Matteo Spagnesi, Azzurra Dallo, Federico Gabrieli, Jacopo De Blasi, Fabrizio Zannoni, Daniele Cairns, Warren R.L. Gambaro, Andrea Barbante, Carlo Anal Chem [Image: see text] The development of new analytical systems and the improvement of the existing ones to obtain high-resolution measurements of chemical markers in samples from ice cores, is one of the main challenges the paleoclimatic scientific community is facing. Different chemical species can be used as markers for tracking emission sources or specific environmental processes. Although some markers, such as methane sulfonic acid (a proxy of marine productivity), are commonly used, there is a lack of data on other organic tracers in ice cores, making their continuous analysis analytically challenging. Here, we present an innovative combination of fast liquid chromatography coupled with tandem mass spectrometry (FLC-MS/MS) to continuously determine organic markers in ice cores. After specific optimization, this approach was applied to the quantification of vanillic and syringic acids, two specific markers for biomass burning. Using the validated method, detection limits of 3.6 and 4.6 pg mL(–1) for vanillic and syringic acids, respectively, were achieved. Thanks to the coupling of FLC-MS/MS with the continuous flow analytical system, we obtained one measurement every 30 s, which corresponds to a sampling resolution of a sample every 1.5 cm with a melting rate of 3.0 cm min(–1). To check the robustness of the method, we analyzed two parallel sticks of an alpine ice core over more than 5 h. Vanillic acid was found with concentrations in the range of picograms per milliliter, suggesting the combustion of coniferous trees, which are found throughout the Italian Alps. American Chemical Society 2022-03-23 2022-04-05 /pmc/articles/PMC8988124/ /pubmed/35319865 http://dx.doi.org/10.1021/acs.analchem.1c05412 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Barbaro, Elena
Feltracco, Matteo
Spagnesi, Azzurra
Dallo, Federico
Gabrieli, Jacopo
De Blasi, Fabrizio
Zannoni, Daniele
Cairns, Warren R.L.
Gambaro, Andrea
Barbante, Carlo
Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores
title Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores
title_full Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores
title_fullStr Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores
title_full_unstemmed Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores
title_short Fast Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Analysis of Vanillic and Syringic Acids in Ice Cores
title_sort fast liquid chromatography coupled with tandem mass spectrometry for the analysis of vanillic and syringic acids in ice cores
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988124/
https://www.ncbi.nlm.nih.gov/pubmed/35319865
http://dx.doi.org/10.1021/acs.analchem.1c05412
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