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Induced Synthesis of Mycolactone Restores the Pathogenesis of Mycobacterium ulcerans In Vitro and In Vivo

Mycobacterium ulcerans is the causative agent of Buruli ulcer (BU), the third most common mycobacterial infection. Virulent M. ulcerans secretes mycolactone, a polyketide toxin. Most observations of M. ulcerans infection are described as an extracellular milieu in the form of a necrotic ulcer. While...

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Detalles Bibliográficos
Autores principales:	Strong, Emily, Hart, Bryan, Wang, Jia, Orozco, Maria Gonzalez, Lee, Sunhee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988146/ https://www.ncbi.nlm.nih.gov/pubmed/35401531 http://dx.doi.org/10.3389/fimmu.2022.750643

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