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COVID-19 induced hypoparathyroidism: A case report
Low levels of serum calcium, elevated levels of serum phosphorus and absent or abnormally low levels of serum parathyroid hormone characterize hypoparathyroidism, a rare endocrine deficiency illness. Hypoparathyroidism is caused by injury to the parathyroid gland as a result of surgery or autoimmune...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988155/ https://www.ncbi.nlm.nih.gov/pubmed/35401797 http://dx.doi.org/10.3892/etm.2022.11276 |
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author | Georgakopoulou, Vasiliki Epameinondas Avramopoulos, Pantelis Papalexis, Petros Bitsani, Aikaterini Damaskos, Christos Garmpi, Anna Venetikou, Maria S. Paramythiotis, Daniel Karlafti, Eleni Sklapani, Pagona Trakas, Nikolaos Spandidos, Demetrios A. |
author_facet | Georgakopoulou, Vasiliki Epameinondas Avramopoulos, Pantelis Papalexis, Petros Bitsani, Aikaterini Damaskos, Christos Garmpi, Anna Venetikou, Maria S. Paramythiotis, Daniel Karlafti, Eleni Sklapani, Pagona Trakas, Nikolaos Spandidos, Demetrios A. |
author_sort | Georgakopoulou, Vasiliki Epameinondas |
collection | PubMed |
description | Low levels of serum calcium, elevated levels of serum phosphorus and absent or abnormally low levels of serum parathyroid hormone characterize hypoparathyroidism, a rare endocrine deficiency illness. Hypoparathyroidism is caused by injury to the parathyroid gland as a result of surgery or autoimmune disease. In addition, hypoparathyroidism may develop due to genetic causes or infiltrative diseases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized by multi-organ involvement, including the dysfunction of endocrine glands. Previous studies have demonstrated that SARS-CoV-2 infection induces endocrine tissue damage via various mechanisms, including direct cell damage from viral entry to the glands by binding to the angiotensin converting enzyme 2 receptors and replication, vasculitis, arterial and venous thrombosis, hypoxic cell damage, immune response and the cytokine storm. The effects of the new coronavirus, coronavirus disease 2019 (COVID-19) on the parathyroid glands have received limited attention. Hypoparathyroidism has been observed in a small number of individuals as a result of SARS-CoV-2 infection. The present study describes the case of a patient with primary hypoparathyroidism induced by COVID-19. Clinicians should also keep in mind that, despite the fact that SARS-CoV-2 has no known tropism for the parathyroid glands, it can result in primary hypoparathyroidism and decompensation of old primary hypoparathyroidism. |
format | Online Article Text |
id | pubmed-8988155 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-89881552022-04-08 COVID-19 induced hypoparathyroidism: A case report Georgakopoulou, Vasiliki Epameinondas Avramopoulos, Pantelis Papalexis, Petros Bitsani, Aikaterini Damaskos, Christos Garmpi, Anna Venetikou, Maria S. Paramythiotis, Daniel Karlafti, Eleni Sklapani, Pagona Trakas, Nikolaos Spandidos, Demetrios A. Exp Ther Med Case Report Low levels of serum calcium, elevated levels of serum phosphorus and absent or abnormally low levels of serum parathyroid hormone characterize hypoparathyroidism, a rare endocrine deficiency illness. Hypoparathyroidism is caused by injury to the parathyroid gland as a result of surgery or autoimmune disease. In addition, hypoparathyroidism may develop due to genetic causes or infiltrative diseases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized by multi-organ involvement, including the dysfunction of endocrine glands. Previous studies have demonstrated that SARS-CoV-2 infection induces endocrine tissue damage via various mechanisms, including direct cell damage from viral entry to the glands by binding to the angiotensin converting enzyme 2 receptors and replication, vasculitis, arterial and venous thrombosis, hypoxic cell damage, immune response and the cytokine storm. The effects of the new coronavirus, coronavirus disease 2019 (COVID-19) on the parathyroid glands have received limited attention. Hypoparathyroidism has been observed in a small number of individuals as a result of SARS-CoV-2 infection. The present study describes the case of a patient with primary hypoparathyroidism induced by COVID-19. Clinicians should also keep in mind that, despite the fact that SARS-CoV-2 has no known tropism for the parathyroid glands, it can result in primary hypoparathyroidism and decompensation of old primary hypoparathyroidism. D.A. Spandidos 2022-05 2022-03-23 /pmc/articles/PMC8988155/ /pubmed/35401797 http://dx.doi.org/10.3892/etm.2022.11276 Text en Copyright: © Epameinondas Georgakopoulou et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Georgakopoulou, Vasiliki Epameinondas Avramopoulos, Pantelis Papalexis, Petros Bitsani, Aikaterini Damaskos, Christos Garmpi, Anna Venetikou, Maria S. Paramythiotis, Daniel Karlafti, Eleni Sklapani, Pagona Trakas, Nikolaos Spandidos, Demetrios A. COVID-19 induced hypoparathyroidism: A case report |
title | COVID-19 induced hypoparathyroidism: A case report |
title_full | COVID-19 induced hypoparathyroidism: A case report |
title_fullStr | COVID-19 induced hypoparathyroidism: A case report |
title_full_unstemmed | COVID-19 induced hypoparathyroidism: A case report |
title_short | COVID-19 induced hypoparathyroidism: A case report |
title_sort | covid-19 induced hypoparathyroidism: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988155/ https://www.ncbi.nlm.nih.gov/pubmed/35401797 http://dx.doi.org/10.3892/etm.2022.11276 |
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