Negative Immune Checkpoint Protein, VISTA, Regulates the CD4(+) T(reg) Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival

Sepsis is a systemic immune response to infection that is responsible for ~35% of in-hospital deaths and over 24 billion dollars in annual treatment costs. Strategic targeting of non-redundant negative immune checkpoint protein pathways can cater therapeutics to the individual septic patient and imp...

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Autores principales: Gray, Chyna C., Biron-Girard, Bethany, Wakeley, Michelle E., Chung, Chun-Shiang, Chen, Yaping, Quiles-Ramirez, Yael, Tolbert, Jessica D., Ayala, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988198/
https://www.ncbi.nlm.nih.gov/pubmed/35401514
http://dx.doi.org/10.3389/fimmu.2022.861670

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