Combination Therapy of Alpha-Lipoic Acid, Gliclazide and Ramipril Protects Against Development of Diabetic Cardiomyopathy via Inhibition of TGF-β/Smad Pathway

Background: Diabetic cardiomyopathy (DCM) is a major long-term complication of diabetes mellitus, accounting for over 20% of annual mortality rate of diabetic patients globally. Although several existing anti-diabetic drugs have improved glycemic status in diabetic patients, prevalence of DCM is sti...

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Detalles Bibliográficos
Autores principales: Dugbartey, George J., Wonje, Quinsker L., Alornyo, Karl K., Robertson, Louis, Adams, Ismaila, Boima, Vincent, Mensah, Samuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988231/
https://www.ncbi.nlm.nih.gov/pubmed/35401218
http://dx.doi.org/10.3389/fphar.2022.850542

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