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The Activation Parameters of a Cold-Adapted Short Chain Dehydrogenase Are Insensitive to Enzyme Oligomerization

[Image: see text] The structural principles of enzyme cold adaptation are of fundamental interest both for understanding protein evolution and for biotechnological applications. It has become clear in recent years that structural flexibility plays a major role in tuning enzyme activity at low temper...

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Detalles Bibliográficos
Autores principales: Koenekoop, Lucien, van der Ent, Florian, Purg, Miha, Åqvist, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988307/
https://www.ncbi.nlm.nih.gov/pubmed/35229609
http://dx.doi.org/10.1021/acs.biochem.2c00024

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