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Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway

BACKGROUND: Chronic myeloid leukemia (CML) is a myeloproliferative tumor originating from hematopoietic stem cells, and resistance to tyrosine kinase inhibitors (TKI) has become a major cause of treatment failure. Alternative drug therapy is one of the important ways to overcome TKI resistance. Hino...

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Detalles Bibliográficos
Autores principales: Qin, Xiang, Chen, Xi, Guo, Ling, Liu, Jing, Yang, You, Zeng, Yan, Li, Cheng, Liu, Wenjun, Ma, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988348/
https://www.ncbi.nlm.nih.gov/pubmed/35387632
http://dx.doi.org/10.1186/s12906-022-03580-7