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Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway
BACKGROUND: Chronic myeloid leukemia (CML) is a myeloproliferative tumor originating from hematopoietic stem cells, and resistance to tyrosine kinase inhibitors (TKI) has become a major cause of treatment failure. Alternative drug therapy is one of the important ways to overcome TKI resistance. Hino...
Autores principales: | Qin, Xiang, Chen, Xi, Guo, Ling, Liu, Jing, Yang, You, Zeng, Yan, Li, Cheng, Liu, Wenjun, Ma, Wenzhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988348/ https://www.ncbi.nlm.nih.gov/pubmed/35387632 http://dx.doi.org/10.1186/s12906-022-03580-7 |
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