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Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation

BACKGROUND: Neuroinflammation in spinal dorsal horn (SDH) plays an important role in the pathogenesis of interstitial cystitis/bladder pain syndrome (IC/BPS). Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) exert potent anti-inflammatory activities in the treatment of various diseases...

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Detalles Bibliográficos
Autores principales:	Zhang, Chi, Huang, Yong, Ouyang, Fubing, Su, Minzhi, Li, Wenbiao, Chen, Jialiang, Xiao, Hengjun, Zhou, Xiangfu, Liu, Bolong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988382/ https://www.ncbi.nlm.nih.gov/pubmed/35387668 http://dx.doi.org/10.1186/s12974-022-02445-7

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