Cargando…
Invasive Pulmonary Aspergillosis after COVID-19 Pneumonia
COVID-19 emerged in China in late 2019 and quickly spread worldwide. The severe immunomodulation and depletion of lymphocytes caused by the virus and its therapy led to an increase in the incidence of superinfections. COVID-19-associated pulmonary aspergillosis (CAPA) is a new entity with increasing...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SMC Media Srl
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988487/ https://www.ncbi.nlm.nih.gov/pubmed/35402341 http://dx.doi.org/10.12890/2022_003209 |
_version_ | 1784682971426455552 |
---|---|
author | David, Filipa Morais, Joana Rodrigues Beires, Francisca Greenfield, Helena Fernandes, Gonçalo L |
author_facet | David, Filipa Morais, Joana Rodrigues Beires, Francisca Greenfield, Helena Fernandes, Gonçalo L |
author_sort | David, Filipa |
collection | PubMed |
description | COVID-19 emerged in China in late 2019 and quickly spread worldwide. The severe immunomodulation and depletion of lymphocytes caused by the virus and its therapy led to an increase in the incidence of superinfections. COVID-19-associated pulmonary aspergillosis (CAPA) is a new entity with increasing incidence and high associated mortality. We present the case of a 68-year-old patient admitted to our ward after recovering from severe COVID-19 pneumonia. Due to worsening of her clinical condition, chest computed tomography was performed and a lung abscess was documented with the identification of Aspergillus niger. Despite therapy with voriconazole, the patient’s condition deteriorated, culminating in her death. LEARNING POINTS: COVID-19-associated pulmonary aspergillosis (CAPA) is a new entity with an increasing incidence. It is a serious and life-threatening complication in patients with severe COVID-19 even in the absence of the classic risk factors for invasive pulmonary aspergillosis. Clinical suspicion is crucial since a timely diagnosis and treatment have a major impact on prognosis. |
format | Online Article Text |
id | pubmed-8988487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SMC Media Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-89884872022-04-08 Invasive Pulmonary Aspergillosis after COVID-19 Pneumonia David, Filipa Morais, Joana Rodrigues Beires, Francisca Greenfield, Helena Fernandes, Gonçalo L Eur J Case Rep Intern Med Articles COVID-19 emerged in China in late 2019 and quickly spread worldwide. The severe immunomodulation and depletion of lymphocytes caused by the virus and its therapy led to an increase in the incidence of superinfections. COVID-19-associated pulmonary aspergillosis (CAPA) is a new entity with increasing incidence and high associated mortality. We present the case of a 68-year-old patient admitted to our ward after recovering from severe COVID-19 pneumonia. Due to worsening of her clinical condition, chest computed tomography was performed and a lung abscess was documented with the identification of Aspergillus niger. Despite therapy with voriconazole, the patient’s condition deteriorated, culminating in her death. LEARNING POINTS: COVID-19-associated pulmonary aspergillosis (CAPA) is a new entity with an increasing incidence. It is a serious and life-threatening complication in patients with severe COVID-19 even in the absence of the classic risk factors for invasive pulmonary aspergillosis. Clinical suspicion is crucial since a timely diagnosis and treatment have a major impact on prognosis. SMC Media Srl 2022-03-02 /pmc/articles/PMC8988487/ /pubmed/35402341 http://dx.doi.org/10.12890/2022_003209 Text en © EFIM 2022 This article is licensed under a Commons Attribution Non-Commercial 4.0 License |
spellingShingle | Articles David, Filipa Morais, Joana Rodrigues Beires, Francisca Greenfield, Helena Fernandes, Gonçalo L Invasive Pulmonary Aspergillosis after COVID-19 Pneumonia |
title | Invasive Pulmonary Aspergillosis after COVID-19 Pneumonia |
title_full | Invasive Pulmonary Aspergillosis after COVID-19 Pneumonia |
title_fullStr | Invasive Pulmonary Aspergillosis after COVID-19 Pneumonia |
title_full_unstemmed | Invasive Pulmonary Aspergillosis after COVID-19 Pneumonia |
title_short | Invasive Pulmonary Aspergillosis after COVID-19 Pneumonia |
title_sort | invasive pulmonary aspergillosis after covid-19 pneumonia |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8988487/ https://www.ncbi.nlm.nih.gov/pubmed/35402341 http://dx.doi.org/10.12890/2022_003209 |
work_keys_str_mv | AT davidfilipa invasivepulmonaryaspergillosisaftercovid19pneumonia AT moraisjoanarodrigues invasivepulmonaryaspergillosisaftercovid19pneumonia AT beiresfrancisca invasivepulmonaryaspergillosisaftercovid19pneumonia AT greenfieldhelena invasivepulmonaryaspergillosisaftercovid19pneumonia AT fernandesgoncalol invasivepulmonaryaspergillosisaftercovid19pneumonia |