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Posttranslational modification of Aurora A‐NSD2 loop contributes to drug resistance in t(4;14) multiple myeloma

BACKGROUND: t(4;14)(p16;q32) cytogenetic abnormality renders high level of histone methyltransferase NSD2 in multiple myeloma (MM) patients, and predicts poor clinical prognosis, but mechanisms of NSD2 in promoting chemoresistance have not been well elucidated. METHODS: An epigenetics compound libra...

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Detalles Bibliográficos
Autores principales:	Jiang, Hongmei, Wang, Yixuan, Wang, Jingjing, Wang, Yafei, Wang, Sheng, He, Enyang, Guo, Jing, Xie, Ying, Wang, Jingya, Li, Xin, Peng, Ziyi, Wang, Mengqi, Hou, Jian, Liu, Zhiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989081/ https://www.ncbi.nlm.nih.gov/pubmed/35389552 http://dx.doi.org/10.1002/ctm2.744

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