Bmi‐1‐RING1B prevents GATA4‐dependent senescence‐associated pathological cardiac hypertrophy by promoting autophagic degradation of GATA4

AIMS: Senescence‐associated pathological cardiac hypertrophy (SA‐PCH) is associated with upregulation of foetal genes, fibrosis, senescence‐associated secretory phenotype (SASP), cardiac dysfunction and increased morbidity and mortality. Therefore, we conducted experiments to investigate whether GAT...

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Detalles Bibliográficos
Autores principales: Chen, Haiyun, Zhou, Jiawen, Chen, Hongjie, Liang, Jialong, Xie, Chunfeng, Gu, Xin, Wang, Rong, Mao, Zhiyuan, Zhang, Yongjie, Li, Qing, Zuo, Guoping, Miao, Dengshun, Jin, Jianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989148/
https://www.ncbi.nlm.nih.gov/pubmed/35390228
http://dx.doi.org/10.1002/ctm2.574

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